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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
6.06
Human Site:
S1160
Identified Species:
10.26
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1160
V
A
E
E
S
M
A
S
A
G
P
E
D
F
E
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
D1024
C
S
L
Y
A
D
S
D
G
E
N
D
S
T
S
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
Dog
Lupus familis
XP_543382
1925
209302
P1168
A
A
D
E
S
M
A
P
V
V
P
D
E
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
P1221
M
A
E
E
S
M
P
P
A
G
G
Q
D
F
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
E31
G
A
F
A
P
G
A
E
E
K
S
I
Y
P
E
Chicken
Gallus gallus
Q5F3P8
2008
223067
D1213
K
A
E
E
S
E
C
D
Q
V
P
E
E
S
I
Frog
Xenopus laevis
Q66J90
1938
216239
T1107
G
Q
E
D
Y
I
E
T
D
R
E
E
D
F
F
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
T1077
T
S
S
S
T
T
S
T
S
S
S
D
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
N976
R
N
L
C
S
G
S
N
E
F
K
K
E
N
V
Honey Bee
Apis mellifera
XP_395451
1406
159180
M742
S
E
S
S
S
E
E
M
S
C
S
E
S
S
N
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
S843
N
Q
S
F
A
S
S
S
R
G
F
Y
R
K
Q
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
P1099
M
P
P
P
S
I
G
P
D
G
L
P
D
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
A649
L
N
P
V
N
H
A
A
K
R
R
K
L
N
I
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
0
0
40
N.A.
66.6
N.A.
N.A.
20
40
26.6
6.6
N.A.
6.6
13.3
13.3
26.6
P-Site Similarity:
100
26.6
0
60
N.A.
80
N.A.
N.A.
20
46.6
46.6
53.3
N.A.
33.3
20
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
36
0
8
15
0
29
8
15
0
0
0
0
0
0
% A
% Cys:
8
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
8
0
15
15
0
0
22
29
8
0
% D
% Glu:
0
8
29
29
0
15
15
8
15
8
8
29
29
8
29
% E
% Phe:
0
0
8
8
0
0
0
0
0
8
8
0
0
29
15
% F
% Gly:
15
0
0
0
0
15
8
0
8
29
8
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
0
0
0
0
8
0
0
15
% I
% Lys:
8
0
0
0
0
0
0
0
8
8
8
15
0
8
8
% K
% Leu:
8
0
15
0
0
0
0
0
0
0
8
0
8
0
0
% L
% Met:
15
0
0
0
0
22
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
15
0
0
8
0
0
8
0
0
8
0
0
15
8
% N
% Pro:
0
8
15
8
8
0
8
22
0
0
22
8
0
8
0
% P
% Gln:
0
15
0
0
0
0
0
0
8
0
0
8
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
0
8
15
8
0
8
0
0
% R
% Ser:
8
15
22
15
50
8
29
15
15
8
22
0
15
15
8
% S
% Thr:
8
0
0
0
8
8
0
15
0
0
0
0
0
8
0
% T
% Val:
8
0
0
8
0
0
0
0
8
15
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _